TumorComparer, updated version GSoC 2021

View the Project on GitHub sanderlab/tumorcomparer

11 July 2021

Week five | TumorComparer on Gene Subsets

by Siras Hakobyan

This week I was calculating comparisons for 10 specified genesets. During the calculation, we detected some technical issues and exceptions which were not covered by package functions. With the help of my mentor, I have updated package functions to handle exceptions and missing values.

Work Progress

  1. TumorComparer on Gene Subsets
    Status։ Done
    Issue: TumorComparer on Gene Subsets

  2. Reproducibility of the results
    Status։ Done
    Issue: Testing Geneset Specific Function

  3. Missing values and exceptions
    Status։ Done
    Issue: Geneset filtering issue

  4. Missing values and exceptions
    Status։ Done
    Issue: Datatypes with zero values in precomputed comparisons

  5. Missing values and exceptions
    Status։ Done
    Issue: Add Test that Triggers to Few Genes in Comparison

  6. Missing values and exceptions
    Status։ Done
    Issue: Comparison function error with LIHC cancer type in TGF-Beta pathway

Conclusion

I have finished precalculation of comparisons for 10 genesets in 23 cancer types, updated package functions to handle missing and zero values. On top of that, I have updated the generalized comparison function to perform comparison for specified gene list.

tags: gsoc - weekly report - coding period